News

In the following, we would like to update you on current changes in the regulatory framework (OECD, ICH and others), inform you on upcoming congresses (including where you can meet us in person) and add information on the company and recent novelties.

“In our own case”

Meet us in Manchester

on 26 August 2025, in "In our own case"

The 53rd Annual Meeting of the European Teratology Society is moving closer and will be held Sept 21-24 2025 at the the Manchester Deansgate Hotel. It would be a great opportunity to meet personally to discuss questions and projects, share ideas and net-work in a nice athmosphere.

Meet us in Cologne

on 03 September 2019, in "In our own case"

The 47th Annual Meeting of the European Teratology Society and the 17th European Congress of Toxicologic Pathology are moving closer and will be held in parallel Sept 17-20 at the Maternushaus in Cologne. It would be a great opportunity to meet personally with Prof. Robert Klopfleisch and Dr. Geertje Lewin, to discuss questions and projects, share

Changes in Company Management

on 20 March 2019, in "In our own case"

Lars Mecklenburg, co-founder of PRECLINICAL SCIENCE, has decided to discontinue consulting. Lars will no longer accept new clients but will be available for existing clients regarding previous projects. His reponsibilities around pathology have been transferred to Robert Klopfleisch and his duties around preclinical drug development projects have been taken over by Roman Föll and Geertje

53rd Annual Meeting of the European Teratology Society

on 26 August 2025, in Dates / Congresses

September 21-24th, the European Teratology Society (ETS) holds its 53rd Annual Meeting in Manchester, UK. For more details check the society’s website at: 53rd Annual Meeting ETS 2025 – European Teratology Society We are proud to co-sponsor the event and would be happy to meet you there.

2022 ETS ReproTox Education Course

on 19 January 2022, in Dates / Congresses

As already in 2021, the European Teratology Society is offering a certified (DGPT, RSB) education Course in Reproductive Toxicology in February 2022. The online course will incorporate basic physiology, specific organ development, guideline requirements and study designs, new science developments and much more. For registration, please visit the society’s website at https://www.etsoc.com/

EUROTOX 2020 postponed

on 30 April 2020, in Dates / Congresses

Yesterday, the decision was made by the EUROTOX Executive Committee to postpone to 2021, the EUROTOX 2020 Copenhagen congress scheduled to take place September 6-9. This was not a decision taken lightly, and a number of options were investigated and discussed in conjunction with the Local Organising Committee (LOC) in Denmark, and the PCO, K.I.T.

OECD Guideline Updates

on 26 August 2025, in Legislative change

In June 2025, the OECD launched a huge package of guideline updates, incl. updates in Section 2 (Effects on Biotic Systems) and Section 4 (Health Effects). 56 new, updated and corrected Test Guidelines (in English and French) were published on 25 June 2025. These guidelines ensure that testing keeps pace with scientific progress and promote

New implementation or update of OECD Guidelines

on 05 September 2019, in Legislative change

Over the last 3 months, a variety of OECD guidelines for in vitro toxicity testing has been newly implemented or updated. The current versions can be downloaded via the PDF link. OECD 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method PDF OECD 432: In Vitro 3T3 NRU Phototoxicity Test PDF OECD 439: In Vitro

New EMA Draft Guideline for Environmental Risk Assessment of Medicinal Products

on 15 January 2019, in Legislative change

At the end of 2018, the European Medicines Agency published the new draft Guideline on the environmental risk assessment of medicinal products for human use for public consultation. Deadline for comments will be 30 June 2019.

Products for parenteral diet in preterm babies – need of light protection

on 05 September 2019, in Worth knowing from the authorities

The following warning was recently issued by the Drug Commission of the German Medical Association concerning parenteral diet in preterm babies. Due to the immaturity of the intestinal tract and immune system, liver metabolism and detoxifying mechanisms, parenteral diet has to be protected from light during storage and treatment. Otherwise these drugs, containing amino acids

EFSA Dietary Reference Values

on 15 January 2019, in Worth knowing from the authorities

The European Food Safety Authority published their “Dietary Reference Values for Nutrients” in a Summary Report. Dietary reference values (DRVs) is an umbrella term for the complete set of nutrient reference values which include population reference intakes (PRIs), the average requirements (ARs), adequate intakes (AIs) and reference intake (RIs) ranges for macronutrients. In 2005, the European

BfS Annual Report 2017/18 published

on 24 November 2018, in Worth knowing from the authorities

The Federal Office for Radiation Protection (BfS) issued its Annual Report 2017/2018, including updates on prevention of UV-associated diseases, on the situation of radiation protection for patients in medicine and on occupational radiation protection.

Analysis of Plant Toxins

on 07 May 2020, in From the science community

The German Society of Toxicology just issued an urgent request for their members. Please consider and reply: Liebe GT-Mitglieder,der operativ/analytische Bereich der ATF Köln (Analytische Task Force bei der Feuerwehr Köln) hat uns kontaktiert und bittet um Mithilfe unserer Gesellschaft für Toxikologie. Die Aufgabe der ATF ist die Unterstützung insb. des Rettungsdienstes und der Feuerwehren, im Einzelfall auch von

New Breakthrough in Orphan Disease Diagnostics?

on 03 February 2020, in From the science community

Any disease affecting fewer than 5 people in 10,000 in the EU is considered rare or an “Orphan Disease”. Although this might appear small, it translates into approximately 246,000 people. Most patients suffer from even rarer diseases affecting 1 person in 100,000 or more. Approximately 5,000-8,000 distinct rare diseases affect 6-8% of the EU population

Dysgeusia after drug treatment

on 05 September 2019, in From the science community

A not so uncommon side effect after drug treatment are changes in taste (dysgeusia) or loss of taste (ageusia). A wide range of drugs may cause these this sensual alteration, including but not limited to anticholinergic drugs, anti-diabetics, sedativa, antibiotics, dopamine receptor antagonists and certain anti-hypertensive drugs. Examples Hypogeusia: Amphotericin B, Carbamazepin, Cisplatin, Diltiazem, Carboplatin, Levodopa,